Clinical Trials

Helping to improve health care services

Clinical trials are essential to the development of new medical treatments and help determine if new medicines are effective, safe and/or better than the current treatments available.  Clinical trials also help to improve health care services by raising standards of treatment. Australian clinical trials are recognised internationally as providing very high-quality patient care.

If you or a member of your family would like to be considered for participation in a clinical trial, please contact us on (08) 9242 7640, email info@affinityresearch.com.au.

ONCOLOGY TRIALS


Bladder Cancer

Open to Recruitment

CheckMate-901: Study of Nivolumab in Combination With Ipilimumab or Standard of Care Chemotherapy Compared to the Standard of Care Chemotherapy Alone in Treatment of Patients With Untreated Inoperable or Metastatic Urothelial Cancer.  For more information, please click here or phone (08) 9242 7640.


Head and Neck Cancer

Open to Recruitment

The SYNERGY-001 Study: A Trial of Intratumoral Injections of SD-101 in Combination With Pembrolizumab in Patients With Metastatic Melanoma or Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma.  For more information, please click here or phone (08) 9242 7640.


Kidney Cancer

Open to Recruitment

CheckMate-9ER: Study of Nivolumab Combined With Cabozantinib Compared to Sunitinib in Previously Untreated Advanced or Metastatic Renal Cell Carcinoma.  For more information, please click here or phone (08) 9242 7640. ACTIVE BUT NOT RECRUITING

Apollo: Trial of the combination of immunotherapy nivolumab with CBT-101 (an oral c-Met inhibitor) in locally advanced or metastatic renal cell carcinoma who have progressed on previous therapy.  For more information, please click here or phone (08) 9242 7640. OPEN TO RECRUITMENT


Liver Cancer

Open to Recruitment

Apollo-1: Trial of the combination of immunotherapy CBT-501 with CBT-101 (an oral c-Met inhibitor) in locally advanced or metastatic hepatocellular carcinoma.  For more information, phone (08) 9242 7640.


Metastatic Melanoma

Closed to Recruitment

The DV3-MEL-01 Study: A Trial of Intratumoral Injections of SD-101 in Combination With Pembrolizumab in Patients With Metastatic Melanoma or Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma.  For more information, please click here or phone (08) 9242 7640.


GASTROENTEROLOGY TRIALS


Crohn’s Disease

Closed to Recruitment

The SERENITY Study: A Study of Mirikizumab (LY3074828) in Participants With Active Crohn’s Disease.  For more information, please click here or phone (08) 9242 7640.


Hereditary Haemochromatosis

Open to Recruitment

LJ401-HH01 – A Phase 2, Multi-Center, Randomized, Placebo-Controlled, Single-Blind Study with LJPC-401 for the Treatment of Iron Overload in Adult Patients with Hereditary Hemochromatosis. For more information, phone (08) 9242 7640


ALZHEIMER’S DISEASE TRIALS


The AWARE Study

Open to Recruitment

A Study to Evaluate the Efficacy and Safety of ABBV-8E12 in Subjects With Early Alzheimer’s Disease. This trial is being conducted by the Australian Alzheimer’s Research Foundation.  Affinity Research is providing nursing support for this study. For more information, please click here or phone (08) 9389 6433 or Email: aarfctd@alzheimers.com.au.


The ENGAGE Trial

Active but not Recruiting

221AD301 Phase 3 Study of Aducanumab (BIIB037) in Early Alzheimer’s Disease.  This trial is being conducted by the Australian Alzheimer’s Research Foundation.  Affinity Research is providing nursing support for this study. For more information, please click here or phone (08) 9389 6433 or Email: aarfctd@alzheimers.com.au.


NEUROLOGY TRIALS


Intragam 10 Observational Study

Closed to Recruitment

CSLCT-IVIG-11-74: A Post-Marketing Safety Study to Evaluate the Occurrence of Aseptic Meningitis Syndrome (AMS) in an Adult Population (>= 18 Years) Treated with Doses of >= 1g/kg Intragam® 10 NF.  For more information, please click here or phone (08) 9446 8726.


Myopathy

Open to Recruitment

The IM101-611 Study: This trial is being conducted by Dr Merrilee Needham, Fiona Stanley Hospital.  Affinity Research is providing nursing support for this study. It is a trial to evaluate the Efficacy and Safety of Abatacept in Combination With Standard Therapy Compared to Standard Therapy Alone in Improving Disease Activity in Adults With Active Idiopathic Inflammatory Myopathy.  For more information, please click here or phone (08) 9242 7640.