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Clinical Trials

Helping to improve health care services



Clinical trials are essential to the development of new medical treatments and help determine if new medicines are effective, safe and/or better than the current treatments available.  Clinical trials also help to improve health care services by raising standards of treatment. Australian clinical trials are recognised internationally as providing very high-quality patient care. More information on clinical trials can be found on our Frequently Asked Questions page.

If you or a member of your family would like to be considered for participation in a clinical trial, contact us on (08) 9242 7640, email info@affinityresearch.com.au, or

ONCOLOGY TRIALS


Bladder Cancer

Open to Recruitment

CHECKMATE-901 Study The purpose of this study is to determine whether an investigational immunotherapy nivolumab in combination with ipilimumab or in combination with standard of care chemotherapy is more effective than standard of care chemotherapy alone in treating patients with previously untreated inoperable or metastatic urothelial cancer. For more information click here.


Head and Neck Cancer

Closed to Recruitment

The SYNERGY-001 Study: A Trial of Intratumoral Injections of SD-101 in Combination With Pembrolizumab in Patients With Metastatic Melanoma or Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma.


Kidney Cancer

Open to Recruitment

Apollo: Trial of the combination of immunotherapy Nivolumab with CBT-101 (an oral c-Met inhibitor) in locally advanced or metastatic renal cell carcinoma who have progressed on previous therapy.  For more information, please click here or phone (08) 9242 7640.

CheckMate-9ER: Study of Nivolumab Combined With Cabozantinib Compared to Sunitinib in Previously Untreated Advanced or Metastatic Renal Cell Carcinoma.  For more information, please click here or phone (08) 9242 7640. ACTIVE BUT NOT RECRUITING


Liver Cancer

Open to Recruitment

Apollo: This is a study to assess the safety and tolerability of the combination of  Genolizumab (also called APL-501 and CBT-501), a PD-1 inhibitor administered concomitantly with CBT-101 (also called APL-101), a c-Met inhibitor, in patients with advanced or metastatic HCC. For more information, click here or phone (08) 9242 7640.


Metastatic Melanoma

Coming soon

The POLARIS Study: An Open-Label, Randomized, Multicenter Trial of Encorafenib + Binimetinib Evaluating a Standard-dose and a High-dose Regimen in Patients With BRAFV600-mutant Melanoma Brain Metastasis.  For more information, please click here or phone (08) 9242 7640.


NEUROLOGY TRIALS


Myositis

Open to Recruitment

The IM101-611 Study: This trial is being conducted by Dr Merrilee Needham, Fiona Stanley Hospital.  Affinity Research is providing nursing support for this study. It is a trial to evaluate the Efficacy and Safety of Abatacept in Combination With Standard Therapy Compared to Standard Therapy Alone in Improving Disease Activity in Adults With Active Idiopathic Inflammatory Myopathy.  For more information, please click here.


GASTROENTEROLOGY TRIALS


Crohn’s Disease

Closed to Recruitment

The SERENITY Study: A Study of Mirikizumab (LY3074828) in Participants With Active Crohn’s Disease.  For more information, please click here or phone (08) 9242 7640.


Hereditary Haemochromatosis

Active but Closed to Recruitment

LJ401-HH01 – A Phase 2, Multi-Center, Randomized, Placebo-Controlled, Single-Blind Study with LJPC-401 for the Treatment of Iron Overload in Adult Patients with Hereditary Hemochromatosis. For more information, see here or fill out our contact form


ALZHEIMER’S DISEASE TRIALS


The AWARE Study

Open to Recruitment

A Study to Evaluate the Efficacy and Safety of ABBV-8E12 in Subjects With Early Alzheimer’s Disease. This trial is being conducted by the Australian Alzheimer’s Research Foundation.  Affinity Research is providing nursing support for this study. For more information, please click here or phone (08) 9389 6433 or Email: aarfctd@alzheimers.com.au.